I have a feeling there are a good number of humans who know about and are friends with wesen. And as often as Monroe and Rosalee woged, I think there are a good many humans who know and just aren't talking about it. It's really a shame the producers took the approach that true humans were just too sensitive, insecure, whatever, to be able to deal with the prospect of sharing the world with wesen.
The best way to frustrate a cyberbully is to ignore him.